Molecular profiling of immunoglobulin heavy-chain gene rearrangements unveils new potential prognostic markers for multiple myeloma patients

Multiple myeloma is a heterogeneous disease whose pathogenesis has not been completely elucidated. Although B-cell receptors play a crucial role in myeloma pathogenesis, the impact of clonal immunoglobulin heavy-chain features in the outcome has not been extensively explored. Here we present the cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Medina, Alejandro, Jiménez, Cristina, Sarasquete, M. Eugenia, González, Marcos, Chillón, M. Carmen, Balanzategui, Ana, Prieto-Conde, Isabel, García-Álvarez, María, Puig, Noemí, González-Calle, Verónica, Alcoceba, Miguel, Cuenca, Isabel, Barrio, Santiago, Escalante, Fernando, Gutiérrez, Norma C., Gironella, Mercedes, Hernández, Miguel T., Sureda, Anna, Oriol, Albert, Bladé, Joan, Lahuerta, Juan-José, San Miguel, Jesús F., Mateos, María-Victoria, Martínez-López, Joaquín, Calasanz, María-José, García-Sanz, Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004993/
https://www.ncbi.nlm.nih.gov/pubmed/32029700
http://dx.doi.org/10.1038/s41408-020-0283-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004993/
https://www.ncbi.nlm.nih.gov/pubmed/32029700
http://dx.doi.org/10.1038/s41408-020-0283-8

Ejemplares similares