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Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia
Late-life depression is associated with an increased risk for dementia but we have limited knowledge of the molecular mechanisms underlying this association. Here we investigated whether brain microRNAs, important posttranscriptional regulators of gene expression, contribute to this association. Lat...
Autores principales: | Wingo, Thomas S., Yang, Jingjing, Fan, Wen, Min Canon, Se, Gerasimov, Ekaterina Sergeevna, Lori, Adriana, Logsdon, Benjamin, Yao, Bing, Seyfried, Nicholas T., Lah, James J., Levey, Allan I., Boyle, Patricia A., Schneider, Julia A., De Jager, Philip L., Bennett, David A., Wingo, Aliza P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004995/ https://www.ncbi.nlm.nih.gov/pubmed/32047652 http://dx.doi.org/10.1038/s41525-019-0113-8 |
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