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Perpendicular alignment of lymphatic endothelial cells in response to spatial gradients in wall shear stress
One-way valves in the lymphatic system form from lymphatic endothelial cells (LECs) during embryonic development and are required for efficient tissue drainage. Although fluid flow is thought to guide both valve formation and maintenance, how this occurs at a mechanistic level remains incompletely u...
Autores principales: | Michalaki, Eleftheria, Surya, Vinay N., Fuller, Gerald G., Dunn, Alexander R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005002/ https://www.ncbi.nlm.nih.gov/pubmed/32029852 http://dx.doi.org/10.1038/s42003-019-0732-8 |
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