Cargando…
On the relevance of cocaine detection in a fingerprint
The finding that drugs and metabolites can be detected from fingerprints is of potential relevance to forensic science and as well as toxicology and clinical testing. However, discriminating between dermal contact and ingestion of drugs has never been verified experimentally. The inability to interp...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005170/ https://www.ncbi.nlm.nih.gov/pubmed/32029797 http://dx.doi.org/10.1038/s41598-020-58856-0 |
_version_ | 1783494877536845824 |
---|---|
author | Jang, M. Costa, C. Bunch, J. Gibson, B. Ismail, M. Palitsin, V. Webb, R. Hudson, M. Bailey, M. J. |
author_facet | Jang, M. Costa, C. Bunch, J. Gibson, B. Ismail, M. Palitsin, V. Webb, R. Hudson, M. Bailey, M. J. |
author_sort | Jang, M. |
collection | PubMed |
description | The finding that drugs and metabolites can be detected from fingerprints is of potential relevance to forensic science and as well as toxicology and clinical testing. However, discriminating between dermal contact and ingestion of drugs has never been verified experimentally. The inability to interpret the result of finding a drug or metabolite in a fingerprint has prevented widespread adoption of fingerprints in drug testing and limits the probative value of detecting drugs in fingermarks. A commonly held belief is that the detection of metabolites of drugs of abuse in fingerprints can be used to confirm a drug has been ingested. However, we show here that cocaine and its primary metabolite, benzoylecgonine, can be detected in fingerprints of non-drug users after contact with cocaine. Additionally, cocaine was found to persist above environmental levels for up to 48 hours after contact. Therefore the detection of cocaine and benzoylecgonine (BZE) in fingermarks can be forensically significant, but do not demonstrate that a person has ingested the substance. In contrast, the data here shows that a drug test from a fingerprint (where hands can be washed prior to donating a sample) CAN distinguish between contact and ingestion of cocaine. If hands were washed prior to giving a fingerprint, BZE was detected only after the administration of cocaine. Therefore BZE can be used to distinguish cocaine contact from cocaine ingestion, provided donors wash their hands prior to sampling. A test based on the detection of BZE in at least one of two donated fingerprint samples has accuracy 95%, sensitivity 90% and specificity of 100% (n = 86). |
format | Online Article Text |
id | pubmed-7005170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-70051702020-02-18 On the relevance of cocaine detection in a fingerprint Jang, M. Costa, C. Bunch, J. Gibson, B. Ismail, M. Palitsin, V. Webb, R. Hudson, M. Bailey, M. J. Sci Rep Article The finding that drugs and metabolites can be detected from fingerprints is of potential relevance to forensic science and as well as toxicology and clinical testing. However, discriminating between dermal contact and ingestion of drugs has never been verified experimentally. The inability to interpret the result of finding a drug or metabolite in a fingerprint has prevented widespread adoption of fingerprints in drug testing and limits the probative value of detecting drugs in fingermarks. A commonly held belief is that the detection of metabolites of drugs of abuse in fingerprints can be used to confirm a drug has been ingested. However, we show here that cocaine and its primary metabolite, benzoylecgonine, can be detected in fingerprints of non-drug users after contact with cocaine. Additionally, cocaine was found to persist above environmental levels for up to 48 hours after contact. Therefore the detection of cocaine and benzoylecgonine (BZE) in fingermarks can be forensically significant, but do not demonstrate that a person has ingested the substance. In contrast, the data here shows that a drug test from a fingerprint (where hands can be washed prior to donating a sample) CAN distinguish between contact and ingestion of cocaine. If hands were washed prior to giving a fingerprint, BZE was detected only after the administration of cocaine. Therefore BZE can be used to distinguish cocaine contact from cocaine ingestion, provided donors wash their hands prior to sampling. A test based on the detection of BZE in at least one of two donated fingerprint samples has accuracy 95%, sensitivity 90% and specificity of 100% (n = 86). Nature Publishing Group UK 2020-02-06 /pmc/articles/PMC7005170/ /pubmed/32029797 http://dx.doi.org/10.1038/s41598-020-58856-0 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Jang, M. Costa, C. Bunch, J. Gibson, B. Ismail, M. Palitsin, V. Webb, R. Hudson, M. Bailey, M. J. On the relevance of cocaine detection in a fingerprint |
title | On the relevance of cocaine detection in a fingerprint |
title_full | On the relevance of cocaine detection in a fingerprint |
title_fullStr | On the relevance of cocaine detection in a fingerprint |
title_full_unstemmed | On the relevance of cocaine detection in a fingerprint |
title_short | On the relevance of cocaine detection in a fingerprint |
title_sort | on the relevance of cocaine detection in a fingerprint |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005170/ https://www.ncbi.nlm.nih.gov/pubmed/32029797 http://dx.doi.org/10.1038/s41598-020-58856-0 |
work_keys_str_mv | AT jangm ontherelevanceofcocainedetectioninafingerprint AT costac ontherelevanceofcocainedetectioninafingerprint AT bunchj ontherelevanceofcocainedetectioninafingerprint AT gibsonb ontherelevanceofcocainedetectioninafingerprint AT ismailm ontherelevanceofcocainedetectioninafingerprint AT palitsinv ontherelevanceofcocainedetectioninafingerprint AT webbr ontherelevanceofcocainedetectioninafingerprint AT hudsonm ontherelevanceofcocainedetectioninafingerprint AT baileymj ontherelevanceofcocainedetectioninafingerprint |