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Identifying multi-hit carcinogenic gene combinations: Scaling up a weighted set cover algorithm using compressed binary matrix representation on a GPU
Despite decades of research, effective treatments for most cancers remain elusive. One reason is that different instances of cancer result from different combinations of multiple genetic mutations (hits). Therefore, treatments that may be effective in some cases are not effective in others. We previ...
Autores principales: | Al Hajri, Qais, Dash, Sajal, Feng, Wu-chun, Garner, Harold R., Anandakrishnan, Ramu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005272/ https://www.ncbi.nlm.nih.gov/pubmed/32029803 http://dx.doi.org/10.1038/s41598-020-58785-y |
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