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A cathelicidin-related antimicrobial peptide suppresses cardiac hypertrophy induced by pressure overload by regulating IGFR1/PI3K/AKT and TLR9/AMPKα

Cathelicidin-related antimicrobial peptide (CRAMP), an antimicrobial peptide, was reported to protect against myocardial ischemia/reperfusion injury. However, the effect of CRAMP on pressure overload-induced cardiac hypertrophy was unknown. This study explored the role of CRAMP on cardiac hypertroph...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaofang, Chen, Linlin, Zhao, Xiaoyan, Xiao, Lili, Yi, Shanting, Kong, Yawei, Jiang, Yan, Zhang, Jinying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005284/ https://www.ncbi.nlm.nih.gov/pubmed/32029708 http://dx.doi.org/10.1038/s41419-020-2296-4

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