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Screening of potential miRNA therapeutics for the prevention of multi-drug resistance in cancer cells

Chemotherapy, a major cancer treatment approach, suffers seriously from multidrug resistance (MDR), generally caused by innate DNA repair proteins that reverse the DNA modification by anti-cancer therapeutics or trans-membrane efflux proteins that pump anti-cancer therapeutics out of the cytosol. Th...

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Detalles Bibliográficos
Autores principales: Medarova, Zdravka, Pantazopoulos, Pamela, Yoo, Byunghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005303/
https://www.ncbi.nlm.nih.gov/pubmed/32029822
http://dx.doi.org/10.1038/s41598-020-58919-2