Cargando…

Depression after Subarachnoid Hemorrhage: A Systematic Review

BACKGROUND AND PURPOSE: Depression is common and debilitating illness accompanying many neurological disorders including non-traumatic subarachnoid hemorrhage (SAH). The aim of this systematic review was to identify and critically appraise all published studies that have reported the frequency, seve...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Wai Kwong, Wang, Lisha, Kwok Chu Wong, George, Ungvari, Gabor S., Yasuno, Fumihiko, Tsoi, Kelvin K.F., Kim, Jong S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Stroke Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005349/
https://www.ncbi.nlm.nih.gov/pubmed/32027789
http://dx.doi.org/10.5853/jos.2019.02103
_version_ 1783494917939527680
author Tang, Wai Kwong
Wang, Lisha
Kwok Chu Wong, George
Ungvari, Gabor S.
Yasuno, Fumihiko
Tsoi, Kelvin K.F.
Kim, Jong S.
author_facet Tang, Wai Kwong
Wang, Lisha
Kwok Chu Wong, George
Ungvari, Gabor S.
Yasuno, Fumihiko
Tsoi, Kelvin K.F.
Kim, Jong S.
author_sort Tang, Wai Kwong
collection PubMed
description BACKGROUND AND PURPOSE: Depression is common and debilitating illness accompanying many neurological disorders including non-traumatic subarachnoid hemorrhage (SAH). The aim of this systematic review was to identify and critically appraise all published studies that have reported the frequency, severity and time course of depression after SAH, the factors associated with its development and the impact of depression on patients’ quality of life after SAH. METHODS: The PubMed database was searched for studies published in English that recruited at least 40 patients (>18 years old) after SAH who were also diagnosed with depression. RESULTS: Altogether 55 studies covering 6,327 patients met study entry criteria. The frequency of depression ranged from 0% to 61.7%, with a weighted proportion of 28.1%. Depression remained common even several years after the index SAH. Depression after SAH was associated with female sex, premorbid depression, anxiety, substance use disorders or any psychiatric disorders, and coping styles. Comorbid cognitive impairment, fatigue, and physical disability also increased the risk of depression. Aneurysmal SAH and infarction may be related to depression as well. Depression reduces the quality of life and life satisfaction in patients after SAH. CONCLUSIONS: Depression is common after SAH and seems to persist. Further research is needed to clarify its time course and identify the neuroendocrine and neurochemical factors and brain circuits associated with the development of post-SAH depression. Randomized controlled treatment trials targeting SAH-related depression are warranted.
format Online
Article
Text
id pubmed-7005349
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Korean Stroke Society
record_format MEDLINE/PubMed
spelling pubmed-70053492020-02-13 Depression after Subarachnoid Hemorrhage: A Systematic Review Tang, Wai Kwong Wang, Lisha Kwok Chu Wong, George Ungvari, Gabor S. Yasuno, Fumihiko Tsoi, Kelvin K.F. Kim, Jong S. J Stroke Review BACKGROUND AND PURPOSE: Depression is common and debilitating illness accompanying many neurological disorders including non-traumatic subarachnoid hemorrhage (SAH). The aim of this systematic review was to identify and critically appraise all published studies that have reported the frequency, severity and time course of depression after SAH, the factors associated with its development and the impact of depression on patients’ quality of life after SAH. METHODS: The PubMed database was searched for studies published in English that recruited at least 40 patients (>18 years old) after SAH who were also diagnosed with depression. RESULTS: Altogether 55 studies covering 6,327 patients met study entry criteria. The frequency of depression ranged from 0% to 61.7%, with a weighted proportion of 28.1%. Depression remained common even several years after the index SAH. Depression after SAH was associated with female sex, premorbid depression, anxiety, substance use disorders or any psychiatric disorders, and coping styles. Comorbid cognitive impairment, fatigue, and physical disability also increased the risk of depression. Aneurysmal SAH and infarction may be related to depression as well. Depression reduces the quality of life and life satisfaction in patients after SAH. CONCLUSIONS: Depression is common after SAH and seems to persist. Further research is needed to clarify its time course and identify the neuroendocrine and neurochemical factors and brain circuits associated with the development of post-SAH depression. Randomized controlled treatment trials targeting SAH-related depression are warranted. Korean Stroke Society 2020-01 2020-01-31 /pmc/articles/PMC7005349/ /pubmed/32027789 http://dx.doi.org/10.5853/jos.2019.02103 Text en Copyright © 2020 Korean Stroke Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Tang, Wai Kwong
Wang, Lisha
Kwok Chu Wong, George
Ungvari, Gabor S.
Yasuno, Fumihiko
Tsoi, Kelvin K.F.
Kim, Jong S.
Depression after Subarachnoid Hemorrhage: A Systematic Review
title Depression after Subarachnoid Hemorrhage: A Systematic Review
title_full Depression after Subarachnoid Hemorrhage: A Systematic Review
title_fullStr Depression after Subarachnoid Hemorrhage: A Systematic Review
title_full_unstemmed Depression after Subarachnoid Hemorrhage: A Systematic Review
title_short Depression after Subarachnoid Hemorrhage: A Systematic Review
title_sort depression after subarachnoid hemorrhage: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005349/
https://www.ncbi.nlm.nih.gov/pubmed/32027789
http://dx.doi.org/10.5853/jos.2019.02103
work_keys_str_mv AT tangwaikwong depressionaftersubarachnoidhemorrhageasystematicreview
AT wanglisha depressionaftersubarachnoidhemorrhageasystematicreview
AT kwokchuwonggeorge depressionaftersubarachnoidhemorrhageasystematicreview
AT ungvarigabors depressionaftersubarachnoidhemorrhageasystematicreview
AT yasunofumihiko depressionaftersubarachnoidhemorrhageasystematicreview
AT tsoikelvinkf depressionaftersubarachnoidhemorrhageasystematicreview
AT kimjongs depressionaftersubarachnoidhemorrhageasystematicreview