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Depression after Subarachnoid Hemorrhage: A Systematic Review
BACKGROUND AND PURPOSE: Depression is common and debilitating illness accompanying many neurological disorders including non-traumatic subarachnoid hemorrhage (SAH). The aim of this systematic review was to identify and critically appraise all published studies that have reported the frequency, seve...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Stroke Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005349/ https://www.ncbi.nlm.nih.gov/pubmed/32027789 http://dx.doi.org/10.5853/jos.2019.02103 |
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author | Tang, Wai Kwong Wang, Lisha Kwok Chu Wong, George Ungvari, Gabor S. Yasuno, Fumihiko Tsoi, Kelvin K.F. Kim, Jong S. |
author_facet | Tang, Wai Kwong Wang, Lisha Kwok Chu Wong, George Ungvari, Gabor S. Yasuno, Fumihiko Tsoi, Kelvin K.F. Kim, Jong S. |
author_sort | Tang, Wai Kwong |
collection | PubMed |
description | BACKGROUND AND PURPOSE: Depression is common and debilitating illness accompanying many neurological disorders including non-traumatic subarachnoid hemorrhage (SAH). The aim of this systematic review was to identify and critically appraise all published studies that have reported the frequency, severity and time course of depression after SAH, the factors associated with its development and the impact of depression on patients’ quality of life after SAH. METHODS: The PubMed database was searched for studies published in English that recruited at least 40 patients (>18 years old) after SAH who were also diagnosed with depression. RESULTS: Altogether 55 studies covering 6,327 patients met study entry criteria. The frequency of depression ranged from 0% to 61.7%, with a weighted proportion of 28.1%. Depression remained common even several years after the index SAH. Depression after SAH was associated with female sex, premorbid depression, anxiety, substance use disorders or any psychiatric disorders, and coping styles. Comorbid cognitive impairment, fatigue, and physical disability also increased the risk of depression. Aneurysmal SAH and infarction may be related to depression as well. Depression reduces the quality of life and life satisfaction in patients after SAH. CONCLUSIONS: Depression is common after SAH and seems to persist. Further research is needed to clarify its time course and identify the neuroendocrine and neurochemical factors and brain circuits associated with the development of post-SAH depression. Randomized controlled treatment trials targeting SAH-related depression are warranted. |
format | Online Article Text |
id | pubmed-7005349 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Korean Stroke Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-70053492020-02-13 Depression after Subarachnoid Hemorrhage: A Systematic Review Tang, Wai Kwong Wang, Lisha Kwok Chu Wong, George Ungvari, Gabor S. Yasuno, Fumihiko Tsoi, Kelvin K.F. Kim, Jong S. J Stroke Review BACKGROUND AND PURPOSE: Depression is common and debilitating illness accompanying many neurological disorders including non-traumatic subarachnoid hemorrhage (SAH). The aim of this systematic review was to identify and critically appraise all published studies that have reported the frequency, severity and time course of depression after SAH, the factors associated with its development and the impact of depression on patients’ quality of life after SAH. METHODS: The PubMed database was searched for studies published in English that recruited at least 40 patients (>18 years old) after SAH who were also diagnosed with depression. RESULTS: Altogether 55 studies covering 6,327 patients met study entry criteria. The frequency of depression ranged from 0% to 61.7%, with a weighted proportion of 28.1%. Depression remained common even several years after the index SAH. Depression after SAH was associated with female sex, premorbid depression, anxiety, substance use disorders or any psychiatric disorders, and coping styles. Comorbid cognitive impairment, fatigue, and physical disability also increased the risk of depression. Aneurysmal SAH and infarction may be related to depression as well. Depression reduces the quality of life and life satisfaction in patients after SAH. CONCLUSIONS: Depression is common after SAH and seems to persist. Further research is needed to clarify its time course and identify the neuroendocrine and neurochemical factors and brain circuits associated with the development of post-SAH depression. Randomized controlled treatment trials targeting SAH-related depression are warranted. Korean Stroke Society 2020-01 2020-01-31 /pmc/articles/PMC7005349/ /pubmed/32027789 http://dx.doi.org/10.5853/jos.2019.02103 Text en Copyright © 2020 Korean Stroke Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Tang, Wai Kwong Wang, Lisha Kwok Chu Wong, George Ungvari, Gabor S. Yasuno, Fumihiko Tsoi, Kelvin K.F. Kim, Jong S. Depression after Subarachnoid Hemorrhage: A Systematic Review |
title | Depression after Subarachnoid Hemorrhage: A Systematic Review |
title_full | Depression after Subarachnoid Hemorrhage: A Systematic Review |
title_fullStr | Depression after Subarachnoid Hemorrhage: A Systematic Review |
title_full_unstemmed | Depression after Subarachnoid Hemorrhage: A Systematic Review |
title_short | Depression after Subarachnoid Hemorrhage: A Systematic Review |
title_sort | depression after subarachnoid hemorrhage: a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005349/ https://www.ncbi.nlm.nih.gov/pubmed/32027789 http://dx.doi.org/10.5853/jos.2019.02103 |
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