Cargando…
Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens
Excessive fat deposition adversely affects poultry production. In this study, we investigated growth, fat deposition, and hepatic mRNA expression of 13 lipid metabolism-related genes in three unique breeds of meat-type chickens with distinct breed origins and genetic relationships. One was Nagoya (N...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japan Poultry Science Association
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005403/ https://www.ncbi.nlm.nih.gov/pubmed/32055204 http://dx.doi.org/10.2141/jpsa.0180064 |
_version_ | 1783494927168045056 |
---|---|
author | Suzuki, Sae Kobayashi, Misato Murai, Atsushi Tsudzuki, Masaoki Ishikawa, Akira |
author_facet | Suzuki, Sae Kobayashi, Misato Murai, Atsushi Tsudzuki, Masaoki Ishikawa, Akira |
author_sort | Suzuki, Sae |
collection | PubMed |
description | Excessive fat deposition adversely affects poultry production. In this study, we investigated growth, fat deposition, and hepatic mRNA expression of 13 lipid metabolism-related genes in three unique breeds of meat-type chickens with distinct breed origins and genetic relationships. One was Nagoya (NAG), a native Japanese breed, whereas the others were White Plymouth Rock (WPR) and White Cornish (WC), which have been used worldwide as the parental breeds of common broiler chickens. NAG chickens were phenotypically characterized by slow growth, lean body fat, and high gizzard and liver weights. In contrast, both WC and WPR chickens were characterized by rapid growth but high percentage of subcutaneous fat and abdominal fat weight, resulting from high feed intake. Among the three breeds, WC had the highest percentage of pectoral muscle weight, whereas WPR was the most obese. Among lipid metabolism-related genes, the expression of PPARA, PPARG, and CD36 was mostly associated with obesity. These results provide basic information for quantitative trait locus (QTL) analysis related to growth and fat traits in an F(2) population of the lean NAG breed and the obese WPR breed of meat-type chickens in future. |
format | Online Article Text |
id | pubmed-7005403 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Japan Poultry Science Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-70054032020-02-13 Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens Suzuki, Sae Kobayashi, Misato Murai, Atsushi Tsudzuki, Masaoki Ishikawa, Akira J Poult Sci Full Papers Excessive fat deposition adversely affects poultry production. In this study, we investigated growth, fat deposition, and hepatic mRNA expression of 13 lipid metabolism-related genes in three unique breeds of meat-type chickens with distinct breed origins and genetic relationships. One was Nagoya (NAG), a native Japanese breed, whereas the others were White Plymouth Rock (WPR) and White Cornish (WC), which have been used worldwide as the parental breeds of common broiler chickens. NAG chickens were phenotypically characterized by slow growth, lean body fat, and high gizzard and liver weights. In contrast, both WC and WPR chickens were characterized by rapid growth but high percentage of subcutaneous fat and abdominal fat weight, resulting from high feed intake. Among the three breeds, WC had the highest percentage of pectoral muscle weight, whereas WPR was the most obese. Among lipid metabolism-related genes, the expression of PPARA, PPARG, and CD36 was mostly associated with obesity. These results provide basic information for quantitative trait locus (QTL) analysis related to growth and fat traits in an F(2) population of the lean NAG breed and the obese WPR breed of meat-type chickens in future. Japan Poultry Science Association 2019-04-25 /pmc/articles/PMC7005403/ /pubmed/32055204 http://dx.doi.org/10.2141/jpsa.0180064 Text en 2019, Japan Poultry Science Association. The Journal of Poultry Science is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Full Papers Suzuki, Sae Kobayashi, Misato Murai, Atsushi Tsudzuki, Masaoki Ishikawa, Akira Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens |
title | Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens |
title_full | Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens |
title_fullStr | Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens |
title_full_unstemmed | Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens |
title_short | Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens |
title_sort | characterization of growth, fat deposition, and lipid metabolism-related gene expression in lean and obese meat-type chickens |
topic | Full Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005403/ https://www.ncbi.nlm.nih.gov/pubmed/32055204 http://dx.doi.org/10.2141/jpsa.0180064 |
work_keys_str_mv | AT suzukisae characterizationofgrowthfatdepositionandlipidmetabolismrelatedgeneexpressioninleanandobesemeattypechickens AT kobayashimisato characterizationofgrowthfatdepositionandlipidmetabolismrelatedgeneexpressioninleanandobesemeattypechickens AT muraiatsushi characterizationofgrowthfatdepositionandlipidmetabolismrelatedgeneexpressioninleanandobesemeattypechickens AT tsudzukimasaoki characterizationofgrowthfatdepositionandlipidmetabolismrelatedgeneexpressioninleanandobesemeattypechickens AT ishikawaakira characterizationofgrowthfatdepositionandlipidmetabolismrelatedgeneexpressioninleanandobesemeattypechickens |