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Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms

BACKGROUND: This study aims to report our experience with cerebral aneurysms, which may improve in the treatment with the flow-diverter stent and follow up. METHODS: This study was conducted in a consecutive series of 130 patients. 134 procedures were performed for treating these patients in Hanoi M...

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Autores principales: Binh, Nguyen Thai, Luu, Vu Dang, Thong, Pham Minh, Cuong, Nguyen Ngoc, Anh, Nguyen Quang, Tuan, Tran Anh, Linh, Le Tuan, Thien, Nguyen Tat, Uddin, Md Jamal, Dinh, Thien Chu, Chu, Dinh-Toi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005424/
https://www.ncbi.nlm.nih.gov/pubmed/32055743
http://dx.doi.org/10.1016/j.heliyon.2020.e03356
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author Binh, Nguyen Thai
Luu, Vu Dang
Thong, Pham Minh
Cuong, Nguyen Ngoc
Anh, Nguyen Quang
Tuan, Tran Anh
Linh, Le Tuan
Thien, Nguyen Tat
Uddin, Md Jamal
Dinh, Thien Chu
Chu, Dinh-Toi
author_facet Binh, Nguyen Thai
Luu, Vu Dang
Thong, Pham Minh
Cuong, Nguyen Ngoc
Anh, Nguyen Quang
Tuan, Tran Anh
Linh, Le Tuan
Thien, Nguyen Tat
Uddin, Md Jamal
Dinh, Thien Chu
Chu, Dinh-Toi
author_sort Binh, Nguyen Thai
collection PubMed
description BACKGROUND: This study aims to report our experience with cerebral aneurysms, which may improve in the treatment with the flow-diverter stent and follow up. METHODS: This study was conducted in a consecutive series of 130 patients. 134 procedures were performed for treating these patients in Hanoi Medical University Hospital and Bach Mai Hospital from January 2012 to April 2017. 143 flow diverter stents (Pipeline, FRED and SILK) were used. Aneurysm morphology, stent patency and cerebral parenchyma before and after intervention were analyzed on images of digital subtraction angiography (DSA), computed tomography (CT) and magnetic resonance (MR). The follow-up data after 3–6 months and 12 months were recorded. RESULTS: In 130 patients (31 men, 99 women), aneurysms of internal carotid artery were mostly common (92.6%), especially in cavernous (35.1%) and in para-ophthalmic (40.3%) segments. 83 cases (61.9%) had wide-neck aneurysms, and 16 cases (11.9%) had multiple aneurysms, and only 5 cases (3.7%) had blister-liked aneurysms. Endovascular treatment was successfully performed at rate of 94.8%. In 3 patients, the stent could not be delivered. Mortality and morbidity rates were 1.5% and 3.7%, respectively. MRI and MSCT follow-up at 3 months showed complete or incomplete occlusions of aneurysms was 7.4% or 17.5%, respectively. 3 patients experienced a thromboembolic event (4.3%). CONCLUSIONS: Intracranial aneurysms of cavernous and para-ophthalmic segments of internal carotid artery are mostly common with wide-neck and multi aneurysms. Deployment of flow diverter stent is safe and effective with high rate of successful and low procedural complications.
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spelling pubmed-70054242020-02-13 Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms Binh, Nguyen Thai Luu, Vu Dang Thong, Pham Minh Cuong, Nguyen Ngoc Anh, Nguyen Quang Tuan, Tran Anh Linh, Le Tuan Thien, Nguyen Tat Uddin, Md Jamal Dinh, Thien Chu Chu, Dinh-Toi Heliyon Article BACKGROUND: This study aims to report our experience with cerebral aneurysms, which may improve in the treatment with the flow-diverter stent and follow up. METHODS: This study was conducted in a consecutive series of 130 patients. 134 procedures were performed for treating these patients in Hanoi Medical University Hospital and Bach Mai Hospital from January 2012 to April 2017. 143 flow diverter stents (Pipeline, FRED and SILK) were used. Aneurysm morphology, stent patency and cerebral parenchyma before and after intervention were analyzed on images of digital subtraction angiography (DSA), computed tomography (CT) and magnetic resonance (MR). The follow-up data after 3–6 months and 12 months were recorded. RESULTS: In 130 patients (31 men, 99 women), aneurysms of internal carotid artery were mostly common (92.6%), especially in cavernous (35.1%) and in para-ophthalmic (40.3%) segments. 83 cases (61.9%) had wide-neck aneurysms, and 16 cases (11.9%) had multiple aneurysms, and only 5 cases (3.7%) had blister-liked aneurysms. Endovascular treatment was successfully performed at rate of 94.8%. In 3 patients, the stent could not be delivered. Mortality and morbidity rates were 1.5% and 3.7%, respectively. MRI and MSCT follow-up at 3 months showed complete or incomplete occlusions of aneurysms was 7.4% or 17.5%, respectively. 3 patients experienced a thromboembolic event (4.3%). CONCLUSIONS: Intracranial aneurysms of cavernous and para-ophthalmic segments of internal carotid artery are mostly common with wide-neck and multi aneurysms. Deployment of flow diverter stent is safe and effective with high rate of successful and low procedural complications. Elsevier 2020-02-04 /pmc/articles/PMC7005424/ /pubmed/32055743 http://dx.doi.org/10.1016/j.heliyon.2020.e03356 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Binh, Nguyen Thai
Luu, Vu Dang
Thong, Pham Minh
Cuong, Nguyen Ngoc
Anh, Nguyen Quang
Tuan, Tran Anh
Linh, Le Tuan
Thien, Nguyen Tat
Uddin, Md Jamal
Dinh, Thien Chu
Chu, Dinh-Toi
Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms
title Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms
title_full Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms
title_fullStr Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms
title_full_unstemmed Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms
title_short Flow diverter stent for treatment of cerebral aneurysms: A report of 130 patients with 134 aneurysms
title_sort flow diverter stent for treatment of cerebral aneurysms: a report of 130 patients with 134 aneurysms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005424/
https://www.ncbi.nlm.nih.gov/pubmed/32055743
http://dx.doi.org/10.1016/j.heliyon.2020.e03356
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