Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms

Tissue-specific autoimmune diseases are assumed to arise through malfunction of two checkpoints for immune tolerance: defective elimination of autoreactive T cells in the thymus and activation of these T cells by corresponding autoantigens in the periphery. However, evidence for this model and the o...

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Detalles Bibliográficos
Autores principales: Matsumoto, Minoru, Tsuneyama, Koichi, Morimoto, Junko, Hosomichi, Kazuyoshi, Matsumoto, Mitsuru, Nishijima, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005526/
https://www.ncbi.nlm.nih.gov/pubmed/31586207
http://dx.doi.org/10.1093/intimm/dxz066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005526/
https://www.ncbi.nlm.nih.gov/pubmed/31586207
http://dx.doi.org/10.1093/intimm/dxz066

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