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Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms
Tissue-specific autoimmune diseases are assumed to arise through malfunction of two checkpoints for immune tolerance: defective elimination of autoreactive T cells in the thymus and activation of these T cells by corresponding autoantigens in the periphery. However, evidence for this model and the o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005526/ https://www.ncbi.nlm.nih.gov/pubmed/31586207 http://dx.doi.org/10.1093/intimm/dxz066 |