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Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway
During obesity, macrophages infiltrate the breast tissue leading to low‐grade chronic inflammation, a factor considered responsible for the higher risk of breast cancer associated with obesity. Here, we formally demonstrate that breast epithelial cells acquire malignant properties when exposed to me...
Autores principales: | Wilcz‐Villega, Ewa, Carter, Edward, Ironside, Alastair, Xu, Ruoyan, Mataloni, Isabella, Holdsworth, Julie, Jones, William, Moreno Béjar, Rocío, Uhlik, Lukas, Bentham, Robert B, Godinho, Susana A, Dalli, Jesmond, Grose, Richard, Szabadkai, Gyorgy, Jones, Louise, Hodivala‐Dilke, Kairbaan, Bianchi, Katiuscia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005540/ https://www.ncbi.nlm.nih.gov/pubmed/31930708 http://dx.doi.org/10.15252/emmm.201910491 |
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