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Transforming growth factor-β1-regulated Fas/FasL pathway activation suppresses nucleus pulposus cell apoptosis in an inflammatory environment

Background: During disc degeneration, inflammatory cytokine tumor necrosis factor (TNF)-α is correlated with nucleus pulposus (NP) cell apoptosis. Transforming growth factor (TGF)-β1 has the potential to regenerate degenerative disc. Objective: To investigate the protective role of TGF-β1 against TN...

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Detalles Bibliográficos
Autores principales:	Xie, Jingjing, Li, Bo, Yao, Bing, Zhang, Pingchao, Wang, Lixin, Lu, Hua, Song, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005578/ https://www.ncbi.nlm.nih.gov/pubmed/31808511 http://dx.doi.org/10.1042/BSR20191726

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