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Evidence of positively selected G6PD A‐ allele reduces risk of Plasmodium falciparum infection in African population on Bioko Island

BACKGROUND: Glucose‐6‐phosphate dehydrogenase (G6PD) is an essential enzyme that protects red blood cells from oxidative damage. Although G6PD‐deficient alleles appear to confer a protective effect of malaria, the link with clinical protection against Plasmodium infection is conflicting. METHODS: A...

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Detalles Bibliográficos
Autores principales: Liang, Xue‐Yan, Chen, Jiang‐Tao, Ma, Yan‐Bo, Huang, Hui‐Ying, Xie, Dong‐De, Monte‐Nguba, Santiago‐m, Ehapo, Carlos Salas, Eyi, Urbano Monsuy, Zheng, Yu‐Zhong, Liu, Xiang‐Zhi, Zha, Guang‐Cai, Lin, Li‐Yun, Chen, Wei‐Zhong, Zhou, Xia, Lin, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005621/
https://www.ncbi.nlm.nih.gov/pubmed/31872983
http://dx.doi.org/10.1002/mgg3.1061