Cargando…
Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study
Understanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral and ocular dryness were performed in age- and sex-matched patients with primar...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005680/ https://www.ncbi.nlm.nih.gov/pubmed/32034249 http://dx.doi.org/10.1038/s41598-020-59078-0 |
_version_ | 1783494989125255168 |
---|---|
author | Tashbayev, B. Garen, T. Palm, Ø. Chen, X. Herlofson, B. B. Young, A. Hove, L. H. Rykke, M. Singh, P. B. Aqrawi, L. A. Utheim, Ø. A. Utheim, T. P. Jensen, J. L. |
author_facet | Tashbayev, B. Garen, T. Palm, Ø. Chen, X. Herlofson, B. B. Young, A. Hove, L. H. Rykke, M. Singh, P. B. Aqrawi, L. A. Utheim, Ø. A. Utheim, T. P. Jensen, J. L. |
author_sort | Tashbayev, B. |
collection | PubMed |
description | Understanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral and ocular dryness were performed in age- and sex-matched patients with primary Sjögren’s syndrome (pSS group), non-Sjögren’s syndrome sicca (non-SS group) and healthy controls. General and oral health-related quality of life were investigated with the 36-Item Short Form Health Survey and the 14-Item Oral Health Impact Profile questionnaires, respectively. Subjective symptoms of xerostomia and ocular dryness were recorded using the Summated Xerostomia Inventory and Ocular Surface Disease Index, respectively. Clinical examinations included evaluation of clinical oral dryness scores, candida counts, unstimulated and stimulated saliva secretory rates, tear osmolarity, tear film break-up time, Schirmer I test and ocular surface staining. Both patient groups had pronounced signs and symptoms of xerostomia and ocular dryness. Even though the non-SS patients had less severe clinical signs than the pSS patients, they demonstrated much poorer general and oral health-related quality of life. In conclusion, non-SS patients require more attention in order to improve their quality of life. |
format | Online Article Text |
id | pubmed-7005680 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-70056802020-02-18 Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study Tashbayev, B. Garen, T. Palm, Ø. Chen, X. Herlofson, B. B. Young, A. Hove, L. H. Rykke, M. Singh, P. B. Aqrawi, L. A. Utheim, Ø. A. Utheim, T. P. Jensen, J. L. Sci Rep Article Understanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral and ocular dryness were performed in age- and sex-matched patients with primary Sjögren’s syndrome (pSS group), non-Sjögren’s syndrome sicca (non-SS group) and healthy controls. General and oral health-related quality of life were investigated with the 36-Item Short Form Health Survey and the 14-Item Oral Health Impact Profile questionnaires, respectively. Subjective symptoms of xerostomia and ocular dryness were recorded using the Summated Xerostomia Inventory and Ocular Surface Disease Index, respectively. Clinical examinations included evaluation of clinical oral dryness scores, candida counts, unstimulated and stimulated saliva secretory rates, tear osmolarity, tear film break-up time, Schirmer I test and ocular surface staining. Both patient groups had pronounced signs and symptoms of xerostomia and ocular dryness. Even though the non-SS patients had less severe clinical signs than the pSS patients, they demonstrated much poorer general and oral health-related quality of life. In conclusion, non-SS patients require more attention in order to improve their quality of life. Nature Publishing Group UK 2020-02-07 /pmc/articles/PMC7005680/ /pubmed/32034249 http://dx.doi.org/10.1038/s41598-020-59078-0 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Tashbayev, B. Garen, T. Palm, Ø. Chen, X. Herlofson, B. B. Young, A. Hove, L. H. Rykke, M. Singh, P. B. Aqrawi, L. A. Utheim, Ø. A. Utheim, T. P. Jensen, J. L. Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study |
title | Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study |
title_full | Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study |
title_fullStr | Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study |
title_full_unstemmed | Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study |
title_short | Patients with non-Sjögren’s sicca report poorer general and oral health-related quality of life than patients with Sjögren’s syndrome: a cross-sectional study |
title_sort | patients with non-sjögren’s sicca report poorer general and oral health-related quality of life than patients with sjögren’s syndrome: a cross-sectional study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005680/ https://www.ncbi.nlm.nih.gov/pubmed/32034249 http://dx.doi.org/10.1038/s41598-020-59078-0 |
work_keys_str_mv | AT tashbayevb patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT garent patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT palmø patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT chenx patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT herlofsonbb patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT younga patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT hovelh patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT rykkem patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT singhpb patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT aqrawila patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT utheimøa patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT utheimtp patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy AT jensenjl patientswithnonsjogrenssiccareportpoorergeneralandoralhealthrelatedqualityoflifethanpatientswithsjogrenssyndromeacrosssectionalstudy |