Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis

Fatty acid and triglyceride synthesis increases greatly in response to feeding and insulin. This lipogenic induction involves coordinate transcriptional activation of various enzymes in lipogenic pathway, including fatty acid synthase and glycerol-3-phosphate acyltransferase. Here, we show that JMJD...

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Detalles Bibliográficos
Autores principales: Viscarra, Jose A., Wang, Yuhui, Nguyen, Hai P., Choi, Yoon Gi, Sul, Hei Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005700/
https://www.ncbi.nlm.nih.gov/pubmed/32034158
http://dx.doi.org/10.1038/s41467-020-14617-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005700/
https://www.ncbi.nlm.nih.gov/pubmed/32034158
http://dx.doi.org/10.1038/s41467-020-14617-1

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