De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

Recent evidence demonstrates that novel protein-coding genes can arise de novo from non-genic loci. This evolutionary innovation is thought to be facilitated by the pervasive translation of non-genic transcripts, which exposes a reservoir of variable polypeptides to natural selection. Here, we syste...

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Detalles Bibliográficos
Autores principales: Vakirlis, Nikolaos, Acar, Omer, Hsu, Brian, Castilho Coelho, Nelson, Van Oss, S. Branden, Wacholder, Aaron, Medetgul-Ernar, Kate, Bowman, Ray W., Hines, Cameron P., Iannotta, John, Parikh, Saurin Bipin, McLysaght, Aoife, Camacho, Carlos J., O’Donnell, Allyson F., Ideker, Trey, Carvunis, Anne-Ruxandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005711/
https://www.ncbi.nlm.nih.gov/pubmed/32034123
http://dx.doi.org/10.1038/s41467-020-14500-z

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