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Effect of immediate cold formalin fixation on phosphoprotein IHC tumor biomarker signal in liver tumors using a cold transport device

Phosphoproteins are the key indicators of signaling network pathway activation. Many disease treatment therapies are designed to inhibit these pathways and effective diagnostics are required to evaluate the efficacy of these treatments. Phosphoprotein IHC have been impractical for diagnostics due to...

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Detalles Bibliográficos
Autores principales: Lerch, Melissa L., Kenerson, Heidi L., Chafin, David, Westerhoff, Maria, Theiss, Abbey, Otter, Michael, Yeung, Raymond S., Baird, Geoffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005752/
https://www.ncbi.nlm.nih.gov/pubmed/32034185
http://dx.doi.org/10.1038/s41598-020-58257-3