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“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells
Antigen-specific redirection of immune effector cells with chimeric antigen receptors (CARs) demonstrated high therapeutic potential for targeting cancers of different origins. Beside CAR-T cells, natural killer (NK) cells represent promising alternative effectors that can be combined with CAR techn...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005792/ https://www.ncbi.nlm.nih.gov/pubmed/32034289 http://dx.doi.org/10.1038/s41598-020-59082-4 |