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“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells

Antigen-specific redirection of immune effector cells with chimeric antigen receptors (CARs) demonstrated high therapeutic potential for targeting cancers of different origins. Beside CAR-T cells, natural killer (NK) cells represent promising alternative effectors that can be combined with CAR techn...

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Detalles Bibliográficos
Autores principales: Mitwasi, Nicola, Feldmann, Anja, Arndt, Claudia, Koristka, Stefanie, Berndt, Nicole, Jureczek, Justyna, Loureiro, Liliana R., Bergmann, Ralf, Máthé, Domokos, Hegedüs, Nikolett, Kovács, Tibor, Zhang, Congcong, Oberoi, Pranav, Jäger, Elke, Seliger, Barbara, Rössig, Claudia, Temme, Achim, Eitler, Jiri, Tonn, Torsten, Schmitz, Marc, Hassel, Jessica C., Jäger, Dirk, Wels, Winfried S., Bachmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005792/
https://www.ncbi.nlm.nih.gov/pubmed/32034289
http://dx.doi.org/10.1038/s41598-020-59082-4

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