Cargando…
Determining sequencing depth in a single-cell RNA-seq experiment
An underlying question for virtually all single-cell RNA sequencing experiments is how to allocate the limited sequencing budget: deep sequencing of a few cells or shallow sequencing of many cells? Here we present a mathematical framework which reveals that, for estimating many important gene proper...
Autores principales: | Zhang, Martin Jinye, Ntranos, Vasilis, Tse, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005864/ https://www.ncbi.nlm.nih.gov/pubmed/32034137 http://dx.doi.org/10.1038/s41467-020-14482-y |
Ejemplares similares
-
Fast and accurate single-cell RNA-seq analysis by clustering of transcript-compatibility counts
por: Ntranos, Vasilis, et al.
Publicado: (2016) -
Deterministic column subset selection for single-cell RNA-Seq
por: McCurdy, Shannon R., et al.
Publicado: (2019) -
Impact of sequencing depth in ChIP-seq experiments
por: Jung, Youngsook L., et al.
Publicado: (2014) -
Accuracy of RNA-Seq and its dependence on sequencing depth
por: Cai, Guoshuai, et al.
Publicado: (2012) -
Local sequence and sequencing depth dependent accuracy of RNA-seq reads
por: Cai, Guoshuai, et al.
Publicado: (2017)