Acetylation of XPF by TIP60 facilitates XPF-ERCC1 complex assembly and activation

The XPF-ERCC1 heterodimer is a structure-specific endonuclease that is essential for nucleotide excision repair (NER) and interstrand crosslink (ICL) repair in mammalian cells. However, whether and how XPF binding to ERCC1 is regulated has not yet been established. Here, we show that TIP60, also kno...

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Detalles Bibliográficos
Autores principales: Wang, Jiajia, He, Hanqing, Chen, Binbin, Jiang, Guixing, Cao, Liping, Jiang, Haiping, Zhang, Guofei, Chen, Jianxiang, Huang, Jun, Yang, Bing, Zhou, Chun, Liu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005904/
https://www.ncbi.nlm.nih.gov/pubmed/32034146
http://dx.doi.org/10.1038/s41467-020-14564-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005904/
https://www.ncbi.nlm.nih.gov/pubmed/32034146
http://dx.doi.org/10.1038/s41467-020-14564-x

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