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Regulation of E3 ubiquitin ligases by homotypic and heterotypic assembly
Protein ubiquitylation is essential for the maintenance of cellular homeostasis. E3 ubiquitin ligases are key components of the enzymatic machinery catalyzing the attachment of ubiquitin to substrate proteins. Consequently, enzymatic dysfunction has been associated with medical conditions including...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005916/ https://www.ncbi.nlm.nih.gov/pubmed/32076548 http://dx.doi.org/10.12688/f1000research.21253.1 |