Allo-antibody production after intraarticular administration of mesenchymal stem cells (MSCs) in an equine osteoarthritis model: effect of repeated administration, MSC inflammatory stimulation, and equine leukocyte antigen (ELA) compatibility

BACKGROUND: Antibody production after allogeneic administration of mesenchymal stem cells (MSCs) could impact their clinical application. Proinflammatory priming of MSCs can potentiate their regulatory ability in vivo but increased expression of major histocompatibility complex (MHC) might augment t...

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Detalles Bibliográficos
Autores principales: Barrachina, Laura, Cequier, Alina, Romero, Antonio, Vitoria, Arantza, Zaragoza, Pilar, Vázquez, Francisco José, Rodellar, Clementina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006079/
https://www.ncbi.nlm.nih.gov/pubmed/32028995
http://dx.doi.org/10.1186/s13287-020-1571-8

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