To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis: HAMLETT, a pragmatic multicenter single-blind randomized controlled trial

BACKGROUND: Antipsychotic medication is effective for symptomatic treatment in schizophrenia-spectrum disorders. After symptom remission, continuation of antipsychotic treatment is associated with lower relapse rates and lower symptom severity compared to dose reduction/discontinuation. Therefore, m...

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Detalles Bibliográficos
Autores principales: Begemann, Marieke J. H., Thompson, Ilse A., Veling, Wim, Gangadin, Shiral S., Geraets, Chris N. W., van ‘t Hag, Erna, Müller-Kuperus, Sanne J., Oomen, Priscilla P., Voppel, Alban E., van der Gaag, Mark, Kikkert, Martijn J., Van Os, Jim, Smit, H. Filip E., Knegtering, Rikus H., Wiersma, Sybren, Stouten, Luyken H., Gijsman, Harm J., Wunderink, Lex, Staring, Anton B. P., Veerman, Selene R. T., Mahabir, Amrita G. S., Kurkamp, Jörg, Pijnenborg, Gerdina H. M., Veen, Natalie D., Marcelis, Machteld, Grootens, Koen P., Faber, Gunnar, van Beveren, Nico J., Been, Agaath, van den Brink, Truus, Bak, Maarten, van Amelsvoort, Therese A. M. J., Ruissen, Andrea, Blanke, Christine, Groen, Karin, de Haan, Lieuwe, Sommer, Iris E. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006112/
https://www.ncbi.nlm.nih.gov/pubmed/32033579
http://dx.doi.org/10.1186/s13063-019-3822-5

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