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Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer’s disease animal model

Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by memory loss and the presence of amyloid plaques and neurofibrillary tangles in the patients’ brains. In this study, we investigated the alterations in metabolite profiles of the hippocampal tissues from 6, 8, and...

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Detalles Bibliográficos
Autores principales: Kim, Hyunju, Kim, Bora, Kim, Hye-Sun, Cho, Joo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006216/
https://www.ncbi.nlm.nih.gov/pubmed/32033569
http://dx.doi.org/10.1186/s13041-020-0565-x