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Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry into target cells. For this, MERS-CoV S engages the host cell protein dipeptidyl peptidase 4 (DPP4, CD26) and the interface between M...

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Detalles Bibliográficos
Autores principales:	Kleine-Weber, Hannah, Schroeder, Simon, Krüger, Nadine, Prokscha, Alexander, Naim, Hassan Y., Müller, Marcel A., Drosten, Christian, Pöhlmann, Stefan, Hoffmann, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006675/ https://www.ncbi.nlm.nih.gov/pubmed/31964246 http://dx.doi.org/10.1080/22221751.2020.1713705

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