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NF-κB Duplications in the Promoter-Variant HIV-1C LTR Impact Inflammation Without Altering Viral Replication in the Context of Simian Human Immunodeficiency Viruses and Opioid-Exposure

Recent spread of the promoter variant (4-κB) Human immunodeficiency virus-1 clade C (HIV-1C) strain is attributed to duplication of the Nuclear Factor Kappa B (NF-κB) binding sites and potential increased heroin consumption in India. To study the underlying biology of 4-κB HIV-1C in rhesus macaques,...

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Detalles Bibliográficos
Autores principales:	Dave, Rajnish S., Ali, Haider, Sil, Susmita, Knight, Lindsey A., Pandey, Kabita, Madduri, Lepakshe S. V., Qiu, Fang, Ranga, Udaykumar, Buch, Shilpa, Byrareddy, Siddappa N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006833/ https://www.ncbi.nlm.nih.gov/pubmed/32076422 http://dx.doi.org/10.3389/fimmu.2020.00095

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