Foretinib Inhibits Cancer Stemness and Gastric Cancer Cell Proliferation by Decreasing CD44 and c-MET Signaling

PURPOSE: CD44 isoforms are highly expressed in cancer stem cells, initiating tumor growth and sustaining tumor self-renewal. Among these isoforms, CD44 variant 9 (CD44v9) is overexpressed in chronic inflammation-induced cancer. CD44 and the mesenchymal-to-epithelial transition (MET) receptor tyrosin...

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Detalles Bibliográficos
Autores principales: Sohn, Sung-Hwa, Kim, Bohyun, Sul, Hee Jung, Choi, Bo Youn, Kim, Hyeong Su, Zang, Dae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006849/
https://www.ncbi.nlm.nih.gov/pubmed/32099405
http://dx.doi.org/10.2147/OTT.S226951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006849/
https://www.ncbi.nlm.nih.gov/pubmed/32099405
http://dx.doi.org/10.2147/OTT.S226951

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