Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/MS method for clinical application

A novel LC-MS/MS method was developed for the quantification of the new cyclin dependent kinase inhibitors (CDKIs) palbociclib and ribociclib and the aromatase inhibitor letrozole used in combinatory regimen. The proposed method is appropriate to be applied in clinical practice due to the simple and...

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Detalles Bibliográficos
Autores principales: Posocco, Bianca, Buzzo, Mauro, Poetto, Ariana Soledad, Orleni, Marco, Gagno, Sara, Zanchetta, Martina, Iacuzzi, Valentina, Guardascione, Michela, Puglisi, Fabio, Basile, Debora, Pelizzari, Giacomo, Marangon, Elena, Toffoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006908/
https://www.ncbi.nlm.nih.gov/pubmed/32032379
http://dx.doi.org/10.1371/journal.pone.0228822

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