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Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy

BACKGROUND: Alpha-1-antitrypsin is a protein involved in avoidance of different processes that are seen in diabetic retinopathy pathogenesis. These processes include apoptosis, extracellular matrix remodeling and damage of vessel walls and capillaries. Furthermore, because of its anti-inflammatory e...

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Detalles Bibliográficos
Autores principales:	Potilinski, María Constanza, Ortíz, Gustavo A., Salica, Juan P., López, Emiliano S., Fernández Acquier, Mariano, Chuluyan, Eduardo, Gallo, Juan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006930/ https://www.ncbi.nlm.nih.gov/pubmed/32032388 http://dx.doi.org/10.1371/journal.pone.0228895

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