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Automated High-Throughput Capillary Circular Dichroism and Intrinsic Fluorescence Spectroscopy for Rapid Determination of Protein Structure
[Image: see text] Assessing the physical stability of proteins is one of the most important challenges in the development, manufacture, and formulation of biotherapeutics. Here, we describe a method for combining and automating circular dichroism and intrinsic protein fluorescence spectroscopy. By r...
Autores principales: | Moore-Kelly, Charles, Welsh, John, Rodger, Alison, Dafforn, Tim R., Thomas, Owen R. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006967/ https://www.ncbi.nlm.nih.gov/pubmed/31584804 http://dx.doi.org/10.1021/acs.analchem.9b03259 |
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