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A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation

[Image: see text] Light-oxygen-voltage (LOV) domains are increasingly used to engineer photoresponsive biological systems. While the photochemical cycle is well documented, the allosteric mechanism by which formation of a cysteinyl-flavin adduct leads to activation is unclear. Via replacement of fla...

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Detalles Bibliográficos
Autores principales:	Kalvaitis, Mindaugas E., Johnson, Luke A., Mart, Robert J., Rizkallah, Pierre, Allemann, Rudolf K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007005/ https://www.ncbi.nlm.nih.gov/pubmed/31082213 http://dx.doi.org/10.1021/acs.biochem.9b00255

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