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Pemphigus vegetans with isolated involvement of the nose and chest: rare variant of pemphigus vulgaris

Pemphigus vulgaris is chronic bullous disease that manifests as bullae and erosions of skin and mucosas, with intraepidermal suprabasal cleft formation seen in the histological examination. It has a rare variant called pemphigus vegetans, where vesicles and bullae are replaced by pustular, verrucous...

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Detalles Bibliográficos
Autores principales: Feitoza, Raisa Ilena Caranhas, Santos, Mônica, Schettini, Maria da Conceição Almeida, Ferreira, Silvana de Albuquerque Damasceno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007041/
https://www.ncbi.nlm.nih.gov/pubmed/31644626
http://dx.doi.org/10.1590/abd1806-4841.20198285
Descripción
Sumario:Pemphigus vulgaris is chronic bullous disease that manifests as bullae and erosions of skin and mucosas, with intraepidermal suprabasal cleft formation seen in the histological examination. It has a rare variant called pemphigus vegetans, where vesicles and bullae are replaced by pustular, verrucous and hyperpigmented lesions, mainly in skin folds. The treatment is similar to that for classic pemphigus vulgaris. The authors present an exuberant case of pemphigus vegetans, covering the nose and chest exclusively, without oral or flexural lesions.