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Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries

Environmental remediation efforts in low‐ and middle‐income countries have yet to be evaluated for their cost effectiveness. To address this gap we calculate a cost per Disability Adjusted Life Year (DALY) averted following the environmental remediation of the former lead smelter and adjoining resid...

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Autores principales: Ericson, Bret, Caravanos, Jack, Depratt, Conrado, Santos, Cynthia, Cabral, Mishelle Gomez, Fuller, Richard, Taylor, Mark Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007121/
https://www.ncbi.nlm.nih.gov/pubmed/32159011
http://dx.doi.org/10.1002/2017GH000109
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author Ericson, Bret
Caravanos, Jack
Depratt, Conrado
Santos, Cynthia
Cabral, Mishelle Gomez
Fuller, Richard
Taylor, Mark Patrick
author_facet Ericson, Bret
Caravanos, Jack
Depratt, Conrado
Santos, Cynthia
Cabral, Mishelle Gomez
Fuller, Richard
Taylor, Mark Patrick
author_sort Ericson, Bret
collection PubMed
description Environmental remediation efforts in low‐ and middle‐income countries have yet to be evaluated for their cost effectiveness. To address this gap we calculate a cost per Disability Adjusted Life Year (DALY) averted following the environmental remediation of the former lead smelter and adjoining residential areas in Paraiso de Dios, Haina, the Dominican Republic, executed from 2009 to 2010. The remediation had the effect of lowering surface soil lead concentrations to below 100 mg/kg and measured geometric mean blood lead levels (BLLs) from 20.6 μg/dL to 5.34 ug/dL. Because BLLs for the entire impacted population were not available, we use environmental data to calculate the resulting disease burden. We find that before the intervention 176 people were exposed to elevated environmental lead levels at Paraiso de Dios resulting in mean BLLs of 24.97 (95% CI: 24.45–25.5) in children (0–7 years old) and 13.98 μg/dL (95% CI: 13.03–15) in adults. We calculate that without the intervention these exposures would have resulted in 133 to 1,096 DALYs and that all of these were averted at a cost of USD 392 to 3,238, depending on assumptions made. We use a societal perspective, meaning that we include all costs regardless of by whom they were incurred and estimate costs in 2009 USD. Lead remediation in low‐ and middle‐income countries is cost effective according to World Health Organization thresholds. Further research is required to compare the approach detailed here with other public health interventions.
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spelling pubmed-70071212020-03-10 Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries Ericson, Bret Caravanos, Jack Depratt, Conrado Santos, Cynthia Cabral, Mishelle Gomez Fuller, Richard Taylor, Mark Patrick Geohealth Research Articles Environmental remediation efforts in low‐ and middle‐income countries have yet to be evaluated for their cost effectiveness. To address this gap we calculate a cost per Disability Adjusted Life Year (DALY) averted following the environmental remediation of the former lead smelter and adjoining residential areas in Paraiso de Dios, Haina, the Dominican Republic, executed from 2009 to 2010. The remediation had the effect of lowering surface soil lead concentrations to below 100 mg/kg and measured geometric mean blood lead levels (BLLs) from 20.6 μg/dL to 5.34 ug/dL. Because BLLs for the entire impacted population were not available, we use environmental data to calculate the resulting disease burden. We find that before the intervention 176 people were exposed to elevated environmental lead levels at Paraiso de Dios resulting in mean BLLs of 24.97 (95% CI: 24.45–25.5) in children (0–7 years old) and 13.98 μg/dL (95% CI: 13.03–15) in adults. We calculate that without the intervention these exposures would have resulted in 133 to 1,096 DALYs and that all of these were averted at a cost of USD 392 to 3,238, depending on assumptions made. We use a societal perspective, meaning that we include all costs regardless of by whom they were incurred and estimate costs in 2009 USD. Lead remediation in low‐ and middle‐income countries is cost effective according to World Health Organization thresholds. Further research is required to compare the approach detailed here with other public health interventions. John Wiley and Sons Inc. 2018-02-22 /pmc/articles/PMC7007121/ /pubmed/32159011 http://dx.doi.org/10.1002/2017GH000109 Text en ©2018. The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Ericson, Bret
Caravanos, Jack
Depratt, Conrado
Santos, Cynthia
Cabral, Mishelle Gomez
Fuller, Richard
Taylor, Mark Patrick
Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries
title Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries
title_full Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries
title_fullStr Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries
title_full_unstemmed Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries
title_short Cost Effectiveness of Environmental Lead Risk Mitigation in Low‐ and Middle‐Income Countries
title_sort cost effectiveness of environmental lead risk mitigation in low‐ and middle‐income countries
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007121/
https://www.ncbi.nlm.nih.gov/pubmed/32159011
http://dx.doi.org/10.1002/2017GH000109
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