Cargando…
HLA-DM Stabilizes the Empty MHCII Binding Groove: A Model Using Customized Natural Move Monte Carlo
[Image: see text] MHC class II molecules bind peptides derived from extracellular proteins that have been ingested by antigen-presenting cells and display them to the immune system. Peptide loading occurs within the antigen-presenting cell and is facilitated by HLA-DM. HLA-DM stabilizes the open con...
Autores principales: | Demharter, Samuel, Knapp, Bernhard, Deane, Charlotte, Minary, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007188/ https://www.ncbi.nlm.nih.gov/pubmed/31070900 http://dx.doi.org/10.1021/acs.jcim.9b00104 |
Ejemplares similares
-
Exploring peptide/MHC detachment processes using hierarchical natural move Monte Carlo
por: Knapp, Bernhard, et al.
Publicado: (2016) -
Modeling Functional Motions of Biological Systems by Customized Natural Moves
por: Demharter, Samuel, et al.
Publicado: (2016) -
HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules
por: Denzin, Lisa K., et al.
Publicado: (1996) -
A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing
por: Ferrante, Andrea, et al.
Publicado: (2012) -
Hierarchical natural move Monte Carlo refines flexible RNA structures into cryo-EM densities
por: Chang, Jeng-Yih, et al.
Publicado: (2020)