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HLA-DM Stabilizes the Empty MHCII Binding Groove: A Model Using Customized Natural Move Monte Carlo

[Image: see text] MHC class II molecules bind peptides derived from extracellular proteins that have been ingested by antigen-presenting cells and display them to the immune system. Peptide loading occurs within the antigen-presenting cell and is facilitated by HLA-DM. HLA-DM stabilizes the open con...

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Detalles Bibliográficos
Autores principales: Demharter, Samuel, Knapp, Bernhard, Deane, Charlotte, Minary, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007188/
https://www.ncbi.nlm.nih.gov/pubmed/31070900
http://dx.doi.org/10.1021/acs.jcim.9b00104

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