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Unexpected Roles of a Tether Harboring a Tyrosine Gatekeeper Residue in Modular Nitrite Reductase Catalysis

[Image: see text] It is generally assumed that tethering enhances rates of electron harvesting and delivery to active sites in multidomain enzymes by proximity and sampling mechanisms. Here, we explore this idea in a tethered 3-domain, trimeric copper-containing nitrite reductase. By reverse enginee...

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Detalles Bibliográficos
Autores principales:	Hedison, Tobias M., Shenoy, Rajesh T., Iorgu, Andreea I., Heyes, Derren J., Fisher, Karl, Wright, Gareth S. A., Hay, Sam, Eady, Robert R., Antonyuk, Svetlana V., Hasnain, S. Samar, Scrutton, Nigel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007197/ https://www.ncbi.nlm.nih.gov/pubmed/32051772 http://dx.doi.org/10.1021/acscatal.9b01266

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