Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids

Retinal organoids (ROs) derived from human induced pluripotent stem cells (hiPSCs) provide potential opportunities for studying human retinal development and disorders; however, to what extent ROs recapitulate the epigenetic features of human retinal development is unknown. In this study, we systema...

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Detalles Bibliográficos
Autores principales: Xie, Haohuan, Zhang, Wen, Zhang, Mei, Akhtar, Tasneem, Li, Young, Yi, Wenyang, Sun, Xiao, Zuo, Zuqi, Wei, Min, Fang, Xin, Yao, Ziqin, Dong, Kai, Zhong, Suijuan, Liu, Qiang, Shen, Yong, Wu, Qian, Wang, Xiaoqun, Zhao, Huan, Bao, Jin, Qu, Kun, Xue, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007246/
https://www.ncbi.nlm.nih.gov/pubmed/32083182
http://dx.doi.org/10.1126/sciadv.aay5247

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