Cargando…

Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family

A newly identified microbial rhodopsin, NM-R3, from the marine flavobacterium Nonlabens marinus, was recently shown to drive chloride ion uptake, extending our understanding of the diversity of mechanisms for biological energy conversion. To clarify the mechanism underlying its function, we characte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yun, Ji-Hye, Ohki, Mio, Park, Jae-Hyun, Ishimoto, Naito, Sato-Tomita, Ayana, Lee, Wonbin, Jin, Zeyu, Tame, Jeremy R. H., Shibayama, Naoya, Park, Sam-Yong, Lee, Weontae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007266/ https://www.ncbi.nlm.nih.gov/pubmed/32083178 http://dx.doi.org/10.1126/sciadv.aay2042

Ejemplares similares

Early-stage dynamics of chloride ion–pumping rhodopsin revealed by a femtosecond X-ray laser
por: Yun, Ji-Hye, et al.
Publicado: (2021)

Direct observation of ligand migration within human hemoglobin at work
por: Shibayama, Naoya, et al.
Publicado: (2020)

Crystal structure and functional characterization of a light-driven chloride pump having an NTQ motif
por: Kim, Kuglae, et al.
Publicado: (2016)

Unique Cl(–) pump rhodopsin with close similarity to H(+) pump rhodopsin
por: Kikukawa, Takashi
Publicado: (2021)

Red-shifting mutation of light-driven sodium-pump rhodopsin
por: Inoue, Keiichi, et al.
Publicado: (2019)

Cyanobacterial Light-Driven Proton Pump, Gloeobacter Rhodopsin: Complementarity between Rhodopsin-Based Energy Production and Photosynthesis
por: Choi, Ah Reum, et al.
Publicado: (2014)

Diversity and functional analysis of light‐driven pumping rhodopsins in marine Flavobacteria
por: Kwon, Yong Min, et al.
Publicado: (2015)

Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface
por: Heo, Yunseok, et al.
Publicado: (2022)

Ion-pumping microbial rhodopsins
por: Kandori, Hideki
Publicado: (2015)

Replaceability of Schiff base proton donors in light-driven proton pump rhodopsins
por: Sasaki, Syogo, et al.
Publicado: (2021)

Na(+) Binding and Transport: Insights from Light-Driven Na(+)-Pumping Rhodopsin
por: Yang, Qifan, et al.
Publicado: (2023)

Chimeric Proton-Pumping Rhodopsins Containing the Cytoplasmic Loop of Bovine Rhodopsin
por: Sasaki, Kengo, et al.
Publicado: (2014)

Evolution of rhodopsin ion pumps in haloarchaea
por: Sharma, Adrian K, et al.
Publicado: (2007)

Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2
por: Park, Jae-Hyun, et al.
Publicado: (2023)

A unique clade of light-driven proton-pumping rhodopsins evolved in the cyanobacterial lineage
por: Hasegawa, Masumi, et al.
Publicado: (2020)

Identification of intermediate conformations in the photocycle of the light-driven sodium-pumping rhodopsin KR2
por: Tsujimura, Masaki, et al.
Publicado: (2021)

Multistep conformational changes leading to the gate opening of light-driven sodium pump rhodopsin
por: Sato, Yukino, et al.
Publicado: (2023)

Functional characterization of sodium-pumping rhodopsins with different pumping properties
por: Tsunoda, Satoshi P., et al.
Publicado: (2017)

Structural insights into the HBV receptor and bile acid transporter NTCP
por: Park, Jae-Hyun, et al.
Publicado: (2022)

A single point mutation converts a proton-pumping rhodopsin into a red-shifted, turn-on fluorescent sensor for chloride
por: Tutol, Jasmine N., et al.
Publicado: (2021)

The Role of the NDQ Motif in Sodium-Pumping Rhodopsins
por: Inoue, Keiichi, et al.
Publicado: (2015)

Real-time identification of two substrate-binding intermediates for the light-driven sodium pump rhodopsin
por: Kato, Tomoya, et al.
Publicado: (2021)

Schizorhodopsins: A family of rhodopsins from Asgard archaea that function as light-driven inward H(+) pumps
por: Inoue, Keiichi, et al.
Publicado: (2020)

Structure and mechanisms of sodium-pumping KR2 rhodopsin
por: Kovalev, Kirill, et al.
Publicado: (2019)

The CarO rhodopsin of the fungus Fusarium fujikuroi is a light-driven proton pump that retards spore germination
por: García-Martínez, Jorge, et al.
Publicado: (2015)

A Chimera Na(+)-Pump Rhodopsin as an Effective Optogenetic Silencer
por: Hoque, Mohammad Razuanul, et al.
Publicado: (2016)

Cryo-EM structure of the human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand-binding specificity
por: Heo, Yunseok, et al.
Publicado: (2022)

Functional importance of the oligomer formation of the cyanobacterial H(+) pump Gloeobacter rhodopsin
por: Iizuka, Azusa, et al.
Publicado: (2019)

Ion-pumping microbial rhodopsin protein classification by machine learning approach
por: Selvaraj, Muthu Krishnan, et al.
Publicado: (2023)

Rhodopsin 7–The unusual Rhodopsin in Drosophila
por: Senthilan, Pingkalai R., et al.
Publicado: (2016)

Homopiperazine Derivatives as a Novel Class of Proteasome Inhibitors with a Unique Mode of Proteasome Binding
por: Kikuchi, Jiro, et al.
Publicado: (2013)

Existence of two O-like intermediates in the photocycle of Acetabularia rhodopsin II, a light-driven proton pump from a marine alga
por: Tamogami, Jun, et al.
Publicado: (2017)

Mutations conferring SO(4)(2−) pumping ability on the cyanobacterial anion pump rhodopsin and the resultant unique features of the mutant
por: Doi, Yuhei, et al.
Publicado: (2022)

Temperature Dependency of Proton Pumping Activity for Marine Microbial Rhodopsin from Antartic Ocean
por: Kim, Se-Hwan, et al.
Publicado: (2020)

The Photoreaction of the Proton-Pumping Rhodopsin 1 From the Maize Pathogenic Basidiomycete Ustilago maydis
por: La Greca, Mariafrancesca, et al.
Publicado: (2022)

Voltage Imaging with Engineered Proton-Pumping Rhodopsins: Insights from the Proton Transfer Pathway
por: Meng, Xin, et al.
Publicado: (2023)

THE MOLECULAR WEIGHT OF RHODOPSIN AND THE NATURE OF THE RHODOPSIN-DIGITONIN COMPLEX
por: Hubbard, Ruth
Publicado: (1954)

The Evolutionary Relationship between Microbial Rhodopsins and Metazoan Rhodopsins
por: Shen, Libing, et al.
Publicado: (2013)

Omega Rhodopsins: A Versatile Class of Microbial Rhodopsins
por: Kwon, Soon-Kyeong, et al.
Publicado: (2020)

Retinal–Carotenoid Interactions in a Sodium-Ion-Pumping Rhodopsin: Implications on Oligomerization and Thermal Stability
por: Ghosh, Mihir, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gipl1l7uj61t7mlgo0a6nes28l