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Targeting of temperate phages drives loss of type I CRISPR-Cas systems
Upon infection of their host, temperate phages (viruses that infect bacteria) enter either a lytic or a lysogenic cycle. The former results in bacterial cell lysis and phage release (horizontal transmission), while lysogeny is characterized by integration of the phage in the host genome and dormancy...
Autores principales: | Rollie, Clare, Chevallereau, Anne, Watson, Bridget N.J., Chyou, Te-yuan, Fradet, Olivier, McLeod, Isobel, Fineran, Peter C., Brown, Chris M., Gandon, Sylvain, Westra, Edze R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007301/ https://www.ncbi.nlm.nih.gov/pubmed/31969710 http://dx.doi.org/10.1038/s41586-020-1936-2 |
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