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Dynamic in vitro intestinal barrier model coupled to chip-based liquid chromatography mass spectrometry for oral bioavailability studies
In oral bioavailability studies, evaluation of the absorption and transport of drugs and food components across the intestinal barrier is crucial. Advances in the field of organ-on-a-chip technology have resulted in a dynamic gut-on-a-chip model that better mimics the in vivo microenvironment of the...
Autores principales: | Santbergen, Milou J. C., van der Zande, Meike, Gerssen, Arjen, Bouwmeester, Hans, Nielen, Michel W. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007416/ https://www.ncbi.nlm.nih.gov/pubmed/31865418 http://dx.doi.org/10.1007/s00216-019-02336-6 |
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