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Pharmacokinetics and Target Attainment of Antibiotics in Critically Ill Children: A Systematic Review of Current Literature

BACKGROUND: Pharmacokinetics (PK) are severely altered in critically ill patients due to changes in volume of distribution (Vd) and/or drug clearance (Cl). This affects the target attainment of antibiotics in critically ill children. We aimed to identify gaps in current knowledge and to compare publ...

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Detalles Bibliográficos
Autores principales:	Hartman, Stan J. F., Brüggemann, Roger J., Orriëns, Lynn, Dia, Nada, Schreuder, Michiel F., de Wildt, Saskia N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Systematic Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007426/ https://www.ncbi.nlm.nih.gov/pubmed/31432468 http://dx.doi.org/10.1007/s40262-019-00813-w

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