A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation

Several studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between Posttraumatic Stress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based on antidepressants, including Selective Serotonin Reuptake Inhibito...

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Autores principales: Rossi, Rodolfo, Niolu, Cinzia, Siracusano, Alberto, Rossi, Alessandro, Di Lorenzo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007739/
https://www.ncbi.nlm.nih.gov/pubmed/32047692
http://dx.doi.org/10.1155/2020/2616492
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author Rossi, Rodolfo
Niolu, Cinzia
Siracusano, Alberto
Rossi, Alessandro
Di Lorenzo, Giorgio
author_facet Rossi, Rodolfo
Niolu, Cinzia
Siracusano, Alberto
Rossi, Alessandro
Di Lorenzo, Giorgio
author_sort Rossi, Rodolfo
collection PubMed
description Several studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between Posttraumatic Stress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based on antidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Noradrenaline Reuptake Inhibitors (SNRI) such as Venlafaxine for PTSD. Second-Generation Antipsychotic (SGA) augmentation has shown good outcomes for nonresponsive OCD cases. However, evidence on the use of SGA in PTSD is more limited. In the present paper, we report on comorbid OCD-PTSD successfully treated with aripiprazole augmentation of sertraline. Shared psychopathological and pharmacological aspects of the disorders are discussed.
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spelling pubmed-70077392020-02-11 A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation Rossi, Rodolfo Niolu, Cinzia Siracusano, Alberto Rossi, Alessandro Di Lorenzo, Giorgio Case Rep Psychiatry Case Report Several studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between Posttraumatic Stress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based on antidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Noradrenaline Reuptake Inhibitors (SNRI) such as Venlafaxine for PTSD. Second-Generation Antipsychotic (SGA) augmentation has shown good outcomes for nonresponsive OCD cases. However, evidence on the use of SGA in PTSD is more limited. In the present paper, we report on comorbid OCD-PTSD successfully treated with aripiprazole augmentation of sertraline. Shared psychopathological and pharmacological aspects of the disorders are discussed. Hindawi 2020-01-27 /pmc/articles/PMC7007739/ /pubmed/32047692 http://dx.doi.org/10.1155/2020/2616492 Text en Copyright © 2020 Rodolfo Rossi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rossi, Rodolfo
Niolu, Cinzia
Siracusano, Alberto
Rossi, Alessandro
Di Lorenzo, Giorgio
A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation
title A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation
title_full A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation
title_fullStr A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation
title_full_unstemmed A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation
title_short A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation
title_sort case of comorbid ptsd and posttraumatic ocd treated with sertraline-aripiprazole augmentation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007739/
https://www.ncbi.nlm.nih.gov/pubmed/32047692
http://dx.doi.org/10.1155/2020/2616492
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