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Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML

INTRODUCTION: AML1-ETO produced by t(8;21) abnomality has multiple effects on the leukemogenesis of acute myeloid leukemia (AML). SET domain, bifurcated 2 (SETDB2) can mediate gene silencing by trimethylation of the ninth lysine residue of histone H3 protein (H3K9) of the promoter and has been confi...

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Detalles Bibliográficos
Autores principales:	Mu, Guangfu, Chen, Fangping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007814/ https://www.ncbi.nlm.nih.gov/pubmed/32099474 http://dx.doi.org/10.2147/CMAR.S227036

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