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Three-Dimensional Optical Scanning in Post–kala-azar Dermal Leishmaniasis (PKDL)

Post–kala-azar dermal leishmaniasis may occur after successful treatment of visceral leishmaniasis and is characterized by macules, papules, or nodules in the skin, with varying size. The response to antileishmanial therapy remains difficult to assess because there are presently no reliable biomarke...

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Detalles Bibliográficos
Autores principales: Zijlstra, Eduard E., Liberton, Niels, Musa, Ahmed M., te Slaa, Sjoerd, Wolff, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008339/
https://www.ncbi.nlm.nih.gov/pubmed/31889505
http://dx.doi.org/10.4269/ajtmh.19-0370
Descripción
Sumario:Post–kala-azar dermal leishmaniasis may occur after successful treatment of visceral leishmaniasis and is characterized by macules, papules, or nodules in the skin, with varying size. The response to antileishmanial therapy remains difficult to assess because there are presently no reliable biomarkers. To date, skin lesions are clinically assessed for decrease in size or change in color, which is invariably subjective. Novel 3-dimensional optical scanning devices offer safe and field-adapted methods to objectively assess skin lesions for changes over time in size and color that can be quantified with great accuracy.