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PRMT6 mediates inflammation via activation of the NF-κB/p65 pathway on a cigarette smoke extract-induced murine emphysema model

INTRODUCTION: Smoke-driven lung inflammation is considered to be the major pathophysiology mechanism of Chronic Obstructive Pulmonary Disease (COPD)/emphysema. Protein arginine methyltransferase 6 (PRMT6) is a key epigenetic enzyme, which is related to protecting the tri-methylation of H3K4 (H3K4me3...

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Detalles Bibliográficos
Autores principales:	He, Xue, Li, Tiao, Luo, Lijuan, Zeng, Huihui, Chen, Yan, Cai, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Publishing on behalf of the International Society for the Prevention of Tobacco Induced Diseases (ISPTID) 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008391/ https://www.ncbi.nlm.nih.gov/pubmed/32047419 http://dx.doi.org/10.18332/tid/116413

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