Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage

BACKGROUND: Excitotoxicity is a central pathological pathway in many neurological diseases with blood–brain barrier (BBB) dysfunction. Kainate, an exogenous excitotoxin, induces epilepsy and BBB damage in animal models, but the direct effect of kainate on brain endothelial cells has not been studied...

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Detalles Bibliográficos
Autores principales: Barna, Lilla, Walter, Fruzsina R., Harazin, András, Bocsik, Alexandra, Kincses, András, Tubak, Vilmos, Jósvay, Katalin, Zvara, Ágnes, Campos-Bedolla, Patricia, Deli, Mária A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008534/
https://www.ncbi.nlm.nih.gov/pubmed/32036791
http://dx.doi.org/10.1186/s12987-019-0166-1

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