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Chondrosarcoma of the dorsal spine – A rare case

Chondrosarcomas of the spine are rare tumors and represent <10% of all chondrosarcomas. In the spine, they may arise from vertebral bodies or posterior elements. They may occur in patients ranging from 13 to 78 years of age. Here, we present a case of a 25-year-old female who presented with compl...

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Autores principales: Vaidya, Mihir Mohan, Shenoy, Asha Sharad, Goel, Naina Atul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008663/
https://www.ncbi.nlm.nih.gov/pubmed/32089620
http://dx.doi.org/10.4103/jcvjs.JCVJS_100_19
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author Vaidya, Mihir Mohan
Shenoy, Asha Sharad
Goel, Naina Atul
author_facet Vaidya, Mihir Mohan
Shenoy, Asha Sharad
Goel, Naina Atul
author_sort Vaidya, Mihir Mohan
collection PubMed
description Chondrosarcomas of the spine are rare tumors and represent <10% of all chondrosarcomas. In the spine, they may arise from vertebral bodies or posterior elements. They may occur in patients ranging from 13 to 78 years of age. Here, we present a case of a 25-year-old female who presented with complaints of lower backache, stiffness in both lower limbs, and tingling sensation in the right lower limb. On examination, both power and sensations were decreased below waist. Magnetic resonance imaging spine revealed an extradural lesion at D5 vertebral body level with severe cord compression. We received the mass in multiple fragments which were grayish-white and firm to hard in consistency. Microscopically, a chondroid tumor was seen with cells arranged in lobules in abundant myxoid matrix. The neoplastic chondrocytes were large in size and had bizarre hyperchromatic nuclei. Few binucleate and multinucleate forms were also seen along with occasional atypical mitoses. There was permeation and destruction of the host bone, and the tumor was seen invading the marrow spaces. Few foci showed high cellularity. No osteoid formation was seen by the tumor. The tumor was diagnosed as Chondrosarcoma – Grade II.
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spelling pubmed-70086632020-02-21 Chondrosarcoma of the dorsal spine – A rare case Vaidya, Mihir Mohan Shenoy, Asha Sharad Goel, Naina Atul J Craniovertebr Junction Spine Case Report Chondrosarcomas of the spine are rare tumors and represent <10% of all chondrosarcomas. In the spine, they may arise from vertebral bodies or posterior elements. They may occur in patients ranging from 13 to 78 years of age. Here, we present a case of a 25-year-old female who presented with complaints of lower backache, stiffness in both lower limbs, and tingling sensation in the right lower limb. On examination, both power and sensations were decreased below waist. Magnetic resonance imaging spine revealed an extradural lesion at D5 vertebral body level with severe cord compression. We received the mass in multiple fragments which were grayish-white and firm to hard in consistency. Microscopically, a chondroid tumor was seen with cells arranged in lobules in abundant myxoid matrix. The neoplastic chondrocytes were large in size and had bizarre hyperchromatic nuclei. Few binucleate and multinucleate forms were also seen along with occasional atypical mitoses. There was permeation and destruction of the host bone, and the tumor was seen invading the marrow spaces. Few foci showed high cellularity. No osteoid formation was seen by the tumor. The tumor was diagnosed as Chondrosarcoma – Grade II. Wolters Kluwer - Medknow 2019 2020-01-23 /pmc/articles/PMC7008663/ /pubmed/32089620 http://dx.doi.org/10.4103/jcvjs.JCVJS_100_19 Text en Copyright: © 2020 Journal of Craniovertebral Junction and Spine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Vaidya, Mihir Mohan
Shenoy, Asha Sharad
Goel, Naina Atul
Chondrosarcoma of the dorsal spine – A rare case
title Chondrosarcoma of the dorsal spine – A rare case
title_full Chondrosarcoma of the dorsal spine – A rare case
title_fullStr Chondrosarcoma of the dorsal spine – A rare case
title_full_unstemmed Chondrosarcoma of the dorsal spine – A rare case
title_short Chondrosarcoma of the dorsal spine – A rare case
title_sort chondrosarcoma of the dorsal spine – a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008663/
https://www.ncbi.nlm.nih.gov/pubmed/32089620
http://dx.doi.org/10.4103/jcvjs.JCVJS_100_19
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