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Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis

Cervical cancer is well known to cause metastasis in liver. Not usually they present in a pattern of acute hepatitis with the liver enzymes trending above the range of thousands. Here we present an interesting case of a patient who presented as acute hepatitis in the setting of metastatic cervical c...

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Autores principales: Kundumadam, Shanker, Laharwani, Hansini, Azhikkalayil, Shafeek, Das, Gokul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008751/
https://www.ncbi.nlm.nih.gov/pubmed/32064200
http://dx.doi.org/10.7759/cureus.6620
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author Kundumadam, Shanker
Laharwani, Hansini
Azhikkalayil, Shafeek
Das, Gokul
author_facet Kundumadam, Shanker
Laharwani, Hansini
Azhikkalayil, Shafeek
Das, Gokul
author_sort Kundumadam, Shanker
collection PubMed
description Cervical cancer is well known to cause metastasis in liver. Not usually they present in a pattern of acute hepatitis with the liver enzymes trending above the range of thousands. Here we present an interesting case of a patient who presented as acute hepatitis in the setting of metastatic cervical cancer to the liver. She presented with elevated liver enzymes above thousands. Her imaging studies revealed new metastatic lesions in the liver. She was subsequently started on chemotherapy but unfortunately, two months later developed septic shock and expired. To our knowledge this is the only case describing a malignancy with metastasis to the liver presenting as an acute hepatitis picture. All the other cases that have been described in the literature presented with acute liver failure.
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spelling pubmed-70087512020-02-15 Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis Kundumadam, Shanker Laharwani, Hansini Azhikkalayil, Shafeek Das, Gokul Cureus Internal Medicine Cervical cancer is well known to cause metastasis in liver. Not usually they present in a pattern of acute hepatitis with the liver enzymes trending above the range of thousands. Here we present an interesting case of a patient who presented as acute hepatitis in the setting of metastatic cervical cancer to the liver. She presented with elevated liver enzymes above thousands. Her imaging studies revealed new metastatic lesions in the liver. She was subsequently started on chemotherapy but unfortunately, two months later developed septic shock and expired. To our knowledge this is the only case describing a malignancy with metastasis to the liver presenting as an acute hepatitis picture. All the other cases that have been described in the literature presented with acute liver failure. Cureus 2020-01-10 /pmc/articles/PMC7008751/ /pubmed/32064200 http://dx.doi.org/10.7759/cureus.6620 Text en Copyright © 2020, Kundumadam et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kundumadam, Shanker
Laharwani, Hansini
Azhikkalayil, Shafeek
Das, Gokul
Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis
title Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis
title_full Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis
title_fullStr Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis
title_full_unstemmed Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis
title_short Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis
title_sort metastatic mucinous adenocarcinoma of the cervix presenting as acute hepatitis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008751/
https://www.ncbi.nlm.nih.gov/pubmed/32064200
http://dx.doi.org/10.7759/cureus.6620
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AT azhikkalayilshafeek metastaticmucinousadenocarcinomaofthecervixpresentingasacutehepatitis
AT dasgokul metastaticmucinousadenocarcinomaofthecervixpresentingasacutehepatitis